VAPOR3D, on 10 October 2020 - 01:05 PM, said:
Several people have reported this situation through the Open Rails website and the solution has been to disable the anti-virus checker.
Windows 10 has a built-in anti-virus checker (Windows Defender) and Microsoft updates it on-line. It appears to be getting more aggressive and interfering in products that it used to ignore.
Please disable Windows Defender and try again. Bear in mind that Windows Defender turns itself back on after a few hours.
Let us know the outcome.